Molecular Weight
app. 65 kDa
Alternative Names
theophylline; 1,3-Dimethylxanthine; Theophyllin; Elixophyllin
Purity
chromatography, dialysis
Concentration
1 mg/mL, conjugation ratio is app. 1:10 - 1:40.
Preservative
0.05% sodium azide
Introduction
Theophylline is a natural alkaloid derivative of xanthine isolated from the plants Camellia sinensis and Coffea arabica. Theophylline appears to inhibit phosphodiesterase and prostaglandin production, regulate calcium flux and intracellular calcium distribution, and antagonize adenosine. Physiologically, this agent relaxes bronchial smooth muscle, produces vasodilation (except in cerebral vessels), stimulates the CNS, stimulates cardiac muscle, induces diuresis, and increases gastric acid secretion; it may also suppress inflammation and improve contractility of the diaphragm.
Antigen Description
Theophylline, covalently linked to human serum albumin
Keywords
drug-HSA conjugate, drug-conjugate, theophylline HSA conjugate
Citations
Publication ()
Have you cited DAG160S in a publication?
Let us know and earn a reward for your research.