Human SRGAP3 peptide

Nature

Synthetic

Tag/Conjugate

Unconjugated

SequenceSimilarities

SRGAP2 peptide is a synthetic peptide corresponding to the Internal region of SRGAP2.

Purity

> 95 % by SDS-PAGE.

Format

Lyophilized

Preservative

None

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request.

Reconstitution

SRGAP3 peptide is supplied as 1mg of dried peptide. When the peptide is reconstituted in 1 mL strile water, the concentration will be 1 mg/mL.

Introduction

srGAP3 (SLIT ROBO Rho GTPase-activating protein 3) is a GTPase activating protein (GAP) for the small G protein Rac. It has a putative role in attenuating Rac1 signalling in neurons. srGAP3 is thought to act downstream of the Slit-Robo pathway, which regulates neuronal migration and axonal branching, and play an important role in axonal regeneration after axotomy. It also plays a putative role in severe mental retardation.

Entrez Gene ID

Synonyms

SRGAP3; SLIT-ROBO Rho GTPase activating protein 3; WRP; MEGAP; SRGAP2; ARHGAP14; SLIT-ROBO Rho GTPase-activating protein 3; mental disorder-associated GAP; rho GTPase-activating protein 14; SLIT-ROBO Rho GTPase activating protein 2; WAVE-associated Rac GTPase activating protein;