Product Overview
A DNA sequence encoding the Influenza A virus (A/goose/Guangdong/1/1996(H5N1)) hemagglutinin (Met1-Gln531), termed as HA, was expressed with a polyhistidine tag at the C-terminus.
Molecular Weight
60.1 kDa
Purity
> 85% as determined by SDS-PAGE
Buffer
Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 10 % glycerol, pH 7.4
Storage
Store at -20°C to -80°C
Introduction
Influenza A virus causes influenza in birds and some mammals, and is the only species of influenza virus A. Influenza virus A is a genus of the Orthomyxoviridae family of viruses. Strains of all subtypes of influenza A virus have been isolated from wild birds, although disease is uncommon. Some isolates of influenza A virus cause severe disease both in domestic poultry and, rarely, in humans. Occasionally, viruses are transmitted from wild aquatic birds to domestic poultry, and this may cause an outbreak or give rise to human influenza pandemics.
Keywords
Influenza A virus; IAV; IAV H5N1; HA
Citations
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Chotpitayasunondh, T; Thisyakorn, U; et al. Safety, Humoral and Cell Mediated Immune Responses to Two Formulations of an Inactivated, Split-Virion Influenza A/H5N1 Vaccine in Children. PLOS ONE 3:-(2008).
Ye, JQ; Shao, HX; et al. Intranasal Delivery of an IgA Monoclonal Antibody Effective against Sublethal H5N1 Influenza Virus Infection in Mice. CLINICAL AND VACCINE IMMUNOLOGY 17:1363-1370(2010).
COA
Certificate of Analysis
