Recombinant Human Cystatin C (Cys-C)

Target

Cystatin C

Nature

Recombinant

Tag/Conjugate

His

Molecular Weight

15 kDa

Purity

> 90 % as determined by SDS-PAGE

Format

Liquid or Lyophilized powder

Buffer

20 mM Tris-HCl, pH=8.0, with 300 mM NaCl and 500 mM Imidazole

Preservative

None

Storage

Store at -20°C to -80°C. Avoid repeated freeze/thaw cycles

Introduction

Cystatin C (Cys C), originally called as gamma-trace and post-gamma-globulin, is a non-glycosylated low molecular weight protein found in many body fluids and secretions. The structure of the Cys C is a composition of five antiparallel β-sheets wrapped around a central helix with the disulfide bonds of between residues 73 and 83 and between residues 97 and 117. The molecular mass of Cys C is 13,343 Da (nonhydroxylated) and 13,359 Da (hydroxylated proline residue at position 3). The isoelectric point of Cys C is 9.3 and thus positively charged in all body fluids.

Keywords

Cystatin C; Cys C; Kidney marker