Terlipressin

Product Overview

Terlipressin

Target

Terlipressin

Nature

Synthetic

Tag/Conjugate

Unconjugated

Purity

Greater than 98.0% as determined by(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.

Format

Sterile Filtered White lyophilized (freeze-dried) powder. The protein (1 mg/ml) was lyophilized with no additives.

Preservative

None

Storage

2-8°C short term, -20°C long term

Introduction

Terlipressin (trade names Teripress by New Medicon Pharma and Glypressin by Ferring Pharmaceuticals) is an analogue of vasopressin used as a vasoactive drug in the management of hypotension. It has been found to be effective when norepinephrine does not help.Indications for use include norepinephrine-resistant septic shock and hepatorenal syndrome. In addition, it is used to treat bleeding esophageal varices.

Keywords

Glycylpressin; Gly-Gly-Gly-[Lys8]vasopressin; Gly-Gly-Gly-L-Cys(1)-L-Tyr-L-Phe-L-Gln-L-Asn-L-Cys(1)-L-Pro-L-Lys-Gly-NH2; Gly-Gly-Gly-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2; [N-α-Triglycyl-8-lysine]-vasopressin; 130: PN: WO2010033207 SEQID: 171 claiMed pr