Batch dependent - please inquire should you have specific requirements
Buffer
20 mM HEPES, 200 mM NaCl, pH 8.0, 20% Glycerol
Preservative
None
Storage
Store at -80°C
Introduction
Threonyl-tRNA synthetase is a member of the aminoacyl-tRNA synthetase family, key enzymes of protein biosynthesis which charge tRNA molecules with the respective amino acids. This 83 kDa protein is an autoantigen recognized by PL-7 antibodies which occur in a subset of patients with polymyositis and dermatomyositis. It could be shown that PL-7 antibodies (similar to Jo-1 antibodies) indicate an increased risk for lung involvement.
Keywords
Threonyl-tRNA Synthetase; TARS; PL-7; Antisynthetase syndrome; ASS
Citations
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