Histrelin [non-species-specific]

Product Overview

Histrelin, non-species-specific

Target

Histrelin

Nature

Synthetic

Tag/Conjugate

Unconjugated

Purity

Greater than 99.0% as determined by: Analysis by RP-HPLC, anion-exchange FPLC, and analysis by reducing and non-reducing SDS-PAGE Silver Stained.

Format

Lyophilized

Concentration

1 mg/mL

Preservative

None

Storage

2-8°C short term, -20°C long term

Introduction

Histrelin acetate is a nonapeptide analog of gonadotropin-releasing hormone (GnRH) with added potency. When present in the bloodstream, it acts on particular cells of the pituitary gland called gonadotropes. Histrelin stimulates these cells to release luteinizing hormone and follicle-stimulating hormone. Thus it is considered a gonadotropin-releasing hormone agonist or GnRH agonist.Histrelin is marketed by Endo Pharmaceuticals under the brand names Vantas and Supprelin LA.

Keywords

Histrelin; Pyr-His-Trp-Ser-Tyr-D-His(Bzl)-Leu-Arg-Pro-NHEt acetate salt; 5-oxo-L-pmlyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-N^^-benzyl-D-histidyl-L-leucyl-L-arginyl-N-ethyl-L-pmlinamide; RWJ-17070; Supprelin; 5-Oxo-L-Pro-L-His-L-Trp-L-Ser-L-Tyr-1-ben