Mouse anti-Chicken BEST1 monoclonal antibody, clone 10D10 targets Chicken Bestrophin-1. The supplied structural record is associated with PDB 4RDQ.
Binds a cytosolic C-terminal surface spanning neighboring Best1 subunits and is remote from the ion-conduction pore. Directly binds Best1 and enabled channel crystallography; later clone-specific studies support channel modulation. Best1 chloride conduction and Ca²⁺ activation are target-protein properties, not antibody performance; deposited Fab expression system was not reported.
Product-specific preparation, formulation, size, storage, and shipping conditions were not specified in the supplied source.
Summary
Specifications
Antibody Isotype
IgG
Clone
10D10
Conjugate
Unconjugated
Applications
Application Notes
IA, ELISA This antibody directly binds Best1 and has enabled crystallographic studies of this ion channel. It is applicable to ion-channel structural biology and Best1 regulation research. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded
General Notes
Directly binds Best1 and enabled channel crystallography; later clone-specific studies support channel modulation. Best1 chloride conduction and Ca²⁺ activation are target-protein properties, not antibody performance; deposited Fab expression system was not reported.
Target
Alternative Names
BEST; TU15B; VMD2
Citations
Publication ()
Have you cited CABT-L2223W in a publication? Let us know and earn a reward for your research.
My Review for Hi-Puri™ Mouse anti-Chicken BEST1 monoclonal antibody, clone 10D10
Creative Diagnostics products are for RESEARCH USE ONLY, please make sure your review is research based.
Required fields are marked with *
Terms and conditions:
We will select high-quality review customers and offer a $30 coupon for your next purchase.
All product reviews must be submitted in the English language.
Creative Diagnostics will not share any personal information of applicants, and all information will be treated with strict confidentiality and will not be sold or disclosed to a third party.
COA
Publication 
Loading ......
