Animals were immunized with particulate murine zonae pellucidae. Spleen cells were fused with Sp2/0 mouse myeloma cells. During development and maturation, mammalian oocytes are surrounded by the zona pellucida, which in the mouse is comprised of three sulfated glycoproteins, ZP1, ZP2 and ZP3. The zona pellucida mediates sperm binding at fertilization, provides a post-fertilization block to polyspermy, and facilitates passage of pre-implantation embryos down the oviduct. The antibody specifically binds to mouse ZP1 glycoprotein.
Morphology
Lymphoblast
Growth Properties
Suspension
CultureMethod
Storage
Liquid nitrogen vapor phase.
Freezing medium: to complete growth medium, add 10%(v/v) DMSO
Target
Synonyms
ZP1; zona pellucida glycoprotein 1; zona pellucida sperm-binding protein 1; zp-1;
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