General Notes
This product (Catalog No. DPATB-H81894) is a rabbit-derived polyclonal antibody raised against human PLCE1. This antibody exhibits cross-reactivity with PLCE1 from mouse, rat, and monkey. It has been affinity purified by Protein A. The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. PLCE1 is a bifunctional enzyme which also regulates small GTPases of the Ras superfamily through its Ras guanine-exchange factor (RasGEF) activity. As an effector of heterotrimeric and small G-protein, it may play a role in cell survival, cell growth, actin organization and T-cell activation.
DPATB-H81894 is suitable for use in WB 1 (500-1:2000), IHC 1 (50-1:200), IF/ICC 1 (100-1:500) applications.
DPATB-H81894 is supplied as a liquid formulation in Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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