Anti-Listeria O IV Polyclonal antibody

The study reports protective role of potential probiotic cultures against infection by biofilm formingCronobacter sakazakiiinCaenorhabditis elegansmodel system. Among the fifteen indigenous potential probiotics, the cell free supernatant ofLactobacillus gastricusBTM7 possessed highest antimicrobial action and biofilm inhibition againstC. sakazakii. The competitive exclusion assays revealed that preconditioning with probiotics resulted in increased mean life span of the nematode to 12-13 days as compared to 5-6 days when the pathogen was administered alone. Enhanced expression of the marker genes (pmk-1, daf-16 and skn-1) was observed during the administration of probiotic cultures. The highest expression of pmk-1 (2.5 folds) was observed with administration ofL. gastricusBTM7. The principal component analysis on selected variables revealed thatL. gastricusBTM7 has the potential to limit the infection ofC. sakazakiiinC. elegansand enhance the expression of key genes involved in extending life span of the worm.

This publication reports the availability of draft genome sequences of 171 Listeria monocytogenes strains isolated from various food-related sources from California between 2007 and 2017. All isolates contain at least two antimicrobial resistance genes.