This gene is specifically expressed in the thymus, and encodes a protein that is localized to the mitochondrion. The expression of this gene is inducible by p53, and it is thought to play an important role in mediating p53-dependent apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]
Function
molecular_function
Synonyms
TP53AIP1; tumor protein p53 regulated apoptosis inducing protein 1; P53AIP1; p53-regulated apoptosis-inducing protein 1
Citations
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