Target
p-aminobenzoic acid
Molecular Weight
app. 44 kDa
Alternative Names
4-aminobenzoic acid; p-aminobenzoic acid; PABA; para-aminobenzoic acid
Purity
chromatography, dialysis
Concentration
1 mg/mL working concentration
Reconstitution
Reconstitute with 1 ml PBS without azide.
Introduction
Aminobenzoic Acid is an organic acid with UV absorption and antifibrotic properties. When exposed to light, aminobenzoic acid (para-aminobenzoic acid or PABA) absorbs UV light and emits excess energy via a photochemical reaction that may cause damage to DNA. Because DNA defects contribute to skin cancer, aminobenzoic acid is no longer widely used in sunscreen formulations. Aminobenzoic acid may also increase oxygen uptake at the tissue level and may enhance monoamine oxidase (MAO) activity to promote the degradation of serotonin, which in excess, may lead to fibrotic changes.
Antigen Description
p-aminobenzoic acid, covalently linked to horseradish peroxidase
Keywords
drug-HRP conjugate, drug-conjugate, p-aminobenzoic acid HRP conjugate
Citations
Publication ()
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