The Newcastle Disease Virus (NDV) Nucleoprotein (NP) is a highly conserved structural protein that encapsidates the viral RNA genome to form the nucleocapsid, which is essential for viral replication, transcription, and assembly. The NP protein interacts with the viral RNA-dependent RNA polymerase complex, serving as a scaffold for RNA synthesis. It is one of the most abundantly expressed proteins during infection and is strongly immunogenic, making it a useful target for diagnostic assays and molecular detection of NDV.
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