Alternative Names
Serum amyloid A; SAA
Purity
> 90% , as determined by SDS-PAGE
Concentration
Batch dependent - please inquire should you have specific requirements.
Buffer
0.02M Tris, pH 7.4
Preservative
0.02% Proclin 300
Storage
Store at ≤-20°C. Avoid repeated freezing and thawing.
Introduction
Serum amyloid A (SAA)proteins are a family of apolipoproteins associated with high-densitylipoprotein (HDL) in plasma. Different isoforms of SAA are expressedconstitutively (constitutive SAAs) at different levels or in response toinflammatory stimuli (acute phase SAAs). These proteins are producedpredominantly by the liver. The conservation of these proteins throughoutinvertebrates and vertebrates suggests that SAAs play a highly essential rolein all animals.
Keywords
Serum amyloid A; SAA; Tumor protein
Citations
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HUSSAIN, R; LUCAS, SB; et al. CLINICAL AND HISTOLOGICAL DISCREPANCIES IN DIAGNOSIS OF ENL REACTIONS CLASSIFIED BY ASSESSMENT OF ACUTE-PHASE PROTEINS SAA AND CRP. INTERNATIONAL JOURNAL OF LEPROSY 63:222-230(1995).
Schulte, S; Sukhova, GK; et al. Genetically programmed biases in Th1 and Th2 immune responses modulate atherogenesis. AMERICAN JOURNAL OF PATHOLOGY 172:1500-1508(2008).