Product Overview
This virus is purified using sucrose density gradient ultracentrifugation, disrupted in the presence of 0.5% Triton X-100 non-ionic detergent/0.6 M KCl, and heat inactivated.
Tag/Conjugate
Unconjugated
Alternative Names
hMPV; Human Metapneumovirus; MPV; Metapneumovirus
Buffer
0.5% Triton X-100 non-ionic detergent/0.6 M KCl
Storage
Viral lysate should be stored at -65°C or below. To avoid repeat freeze-thaws, which could negatively impact product performance, viral lysate should be stored in aliquots upon receipt.
Introduction
Human metapneumovirus (hMPV) is a negative single-stranded RNA virus of the family Paramyxoviridae and is closely related to the avian metapneumovirus (AMPV) subgroup C. It was isolated for the first time in 2001 in the Netherlands by using the RAP-PCR (RNA arbitrarily primed PCR) technique for identification of unknown viruses growing in cultured cells. It may be the second most common cause of lower respiratory infection in young children.
Keywords
hMPV; Human Metapneumovirus; MPV; Metapneumovirus
Inactivation
Heat inactivated. Viral inactivation is verified for every lot of lysate by the absence of viral growth in validated tissue culture based infectivity assays.
Citations
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COA
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