Magic™ Rabbit Anti-Mouse CD163 Monoclonal antibody, clone 351344G5

Antibody Isotype

IgG

Clone

351344G5

Species Reactivity

Mouse

Immunogen

Fusion Protein

Conjugate

Application Notes

We recommend the following antibodies for sandwich immunoassay (Capture - Detection):
DMAB-CPT901 - DMAB-CPT902
Cytometric Bead Array: 0.313-40ng/mL

General Notes

This product (Catalog No. DMAB-CPT902) is a rabbit-derived monoclonal antibody raised against mouse Mouse CD163. It has been affinity purified by Protein A. CD163, also known as M130, is a membrane glycoprotein that belongs to the scavenger receptor superfamily (PMID: 8370408). It is an acute phase-regulated and signal-inducing macrophage protein expressed exclusively in monocytes and tissue macrophages (PMID: 11196644). CD163 mediates endocytosis of haptoglobin-haemoglobin complexes (PMID: 11196644). The uptake of haptoglobin by macrophages contributes to the recycling of iron and also to the inflammatory response (PMID: 22900885). Soluble CD163 (sCD163), as a result of ectodomain shedding during inflammatory activation of macrophages, circulates in blood and has been suggested as a plasma/serum marker for macrophage activity.
DMAB-CPT902 is suitable for use in Cytometric Bead Array (0.313-40ng/mL) application.
DMAB-CPT902 is supplied as a liquid formulation in PBS only. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

Cd163; CD163 antigen; CD163v2; CD163v3

Entrez Gene ID

UniProt ID