Molecular Weight
app. 44 kDa
Alternative Names
mepivacaine; N-(2,6-Dimethylphenyl)-1-methylpiperidine-2-carboxamide; Carbocaine; DL-Mepivacaine; Scandicain
Purity
chromatography, dialysis
Concentration
1 mg/mL working concentration
Reconstitution
Reconstitute with 1 ml PBS without azide.
Introduction
Mepivacaine is an amide-type local anesthetic agent. At the injection site, mepivacaine binds to specific voltage-gated sodium ion channels in neuronal cell membranes, which inhibits both sodium influx and membrane depolarization. This leads to a blockage of nerve impulse initiation and conduction and results in a reversible loss of sensation. Compared to other local anesthetics, this agent has a more rapid onset and moderate duration of action.
Antigen Description
Mepivacaine, covalently linked to horseradish peroxidase
Keywords
drug-HRP conjugate, drug-conjugate, Mepivacaine HRP conjugate
Citations
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