Molecular Weight
app. 65 kDa
Alternative Names
bupivacaine; 1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide 2180-92-9; DL-Bupivacaine; Marcaine; Bupivacaina
Purity
chromatography, dialysis
Concentration
1 mg/mL, conjugation ratio is app. 1:10 - 1:40.
Preservative
0.05% sodium azide
Introduction
Bupivacaine, marketed under the brand name Marcaine among others, is a medication used to decrease feeling in a specific area. Bupivacaine is an amide-type, long-acting local anesthetic. Bupivicaine reversibly binds to specific sodium ion channels in the neuronal membrane, resulting in a decrease in the voltage-dependent membrane permeability to sodium ions and membrane stabilization; inhibition of depolarization and nerve impulse conduction; and a reversible loss of sensation.
Antigen Description
Marcaine, covalently linked to bovine serum albumin
Keywords
drug-BSA conjugate, drug-conjugate, Marcaine BSA conjugate
Citations
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