Specifications
Species Reactivity
Human, Mouse
Immunogen
Recombinant fragment within Human LRRK2 aa 950 to the C-terminus.
Applications
Application Notes
Recommended dilution:
ICC/IF: 1:50
WB: 1:10000-1:50000
Target
Alternative Names
LRRK2; leucine-rich repeat kinase 2; PARK8,Parkinson disease (autosomal dominant) 8; leucine-rich repeat serine/threonine-protein kinase 2; DKFZp434H2111; FLJ45829; RIPK7; ROCO2; augmented in rheumatoid arthritis 17; AURA17; Dardarin; Leucine rich repeat
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.
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Citations
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Hakimi, M; Selvanantham, T; et al. Parkinson's disease-linked LRRK2 is expressed in circulating and tissue immune cells and upregulated following recognition of microbial structures. JOURNAL OF NEURAL TRANSMISSION 118:795-808(2011).
Vitte, J; Traver, S; et al. Leucine-Rich Repeat Kinase 2 Is Associated With the Endoplasmic Reticulum in Dopaminergic Neurons and Accumulates in the Core of Lewy Bodies in Parkinson Disease. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY 69:959-972(2010).