Molecular Weight
app. 65 kDa
Alternative Names
ketoprofen; 2-(3-Benzoylphenyl)propanoic acid; Orudis; 2-(3-Benzoylphenyl)propionic acid
Purity
chromatography, dialysis
Concentration
1 mg/mL, conjugation ratio is app. 1:10 - 1:40.
Preservative
0.05% sodium azide
Introduction
Ketoprofen is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic effects. Ketoprofen inhibits the activity of the enzymes cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. The resulting decrease in prostaglandin synthesis, by prostaglandin synthase, is responsible for the therapeutic effects of ibuprofen. Ketoprofen also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation.
Antigen Description
Ketoprofen, covalently linked to biotinylated human serum albumin
Keywords
drug-HSA-Biotin conjugate, drug-conjugate, Ketoprofen HSA-Biotin conjugate
Citations
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