Recombinant K. pneumoniae Carbapenemase Protein

Nature

Recombinant

Molecular Weight

28 kDa

Alternative Names

Klebsiella pneumoniae Carbapenemase; K. pneumoniae Carbapenemase; KPC; Klebsiella pneumoniae; K. pneumoniae; Carbapenemase

Purity

> 95 % as determined by SDS-PAGE

Format

Liquid

Buffer

PBS

Preservative

None

Storage

Store at -20°C to -80°C. Avoid multiple freeze/thaw cycles

Introduction

Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae have been reported in many countries, and outbreaks due to KPC-producing organisms have been reported worldwide. KPC is an enzyme that degrades penicillin, cephalosporin, and broad-spectrum β-lactams such as the carbapenems. This type of β-lactamase was discovered relatively recently, first detected in a strain isolated in the United States in 1996. The strain was considered a novel β-lactamase able to degrade carbapenem antibiotics; it was classified as a Bush group 2f, class A, serine-β-lactamase and was named KPC.

Keywords

Klebsiella pneumoniae Carbapenemase; K. pneumoniae Carbapenemase; KPC; Klebsiella pneumoniae; K. pneumoniae; Carbapenemase