Rhinoviruses are composed of a capsid that contains four viral proteins VP1, VP2, VP3 and VP4. VP1, VP2, and VP3 form the major part of the protein capsid. The much smaller VP4 protein has a more extended structure and lies at interface between the capsid and the RNA genome. There are 60 copies of each of these proteins assembled as an icosahedron. Antibodies are a major defense against infection with the epitopes lying on the exterior regions of VP1-VP3
Keywords
Rhinovirus; HRV; Rhinovirus C
Inactivation
β-propiolactone (BPL)
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Q: How is DAG-WT1959 Inactivated Human Rhinovirus C Culture Fluid inactivated, and is it suitable for real-time PCR assay development?
A: The standard product is beta-propiolactone-inactivated and is intended for immunoassay or immunization applications. For molecular applications, a heat-inactivated quality-control preparation can be supplied when specified at the time of ordering.
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