Magic™ Rabbit Anti-Human SORBS2 Monoclonal antibody, clone 351134B22

Antibody Isotype

IgG

Clone

351134B22

Species Reactivity

Human

Immunogen

SORBS2 fusion protein

Conjugate

Application Notes

We recommend the following antibodies for sandwich immunoassay (Capture - Detection):
DMAB-CPT815 - DMAB-CPT816

General Notes

This product (Catalog No. DMAB-CPT815) is a rabbit-derived monoclonal antibody raised against human SORBS2. It has been affinity purified by Protein A. SORBS2, also known as ARGBP2, has three C-terminal SH3 domains and an N-terminal sorbin homology (SoHo) domain that interacts with lipid raft proteins. SORBS2 is widely expressed in human tissues and extremely abundant in the heart. In epithelial cells SORBS2 is located in stress fibers and the nucleus; In cardiac muscle cells. SORBS2 is located in the Z-disks of sarcomeres. The subcellular localization suggests that SORBS2 functions as an adapter protein to assemble signaling complexes in stress fibers, and may influence the contractile or elastic properties of cardiac sarcomeres(PMID: 9211900). Alternate splicing results in multiple transcript variants.
DMAB-CPT815 is suitable for use in CBA(Cap), ELISA(Cap) applications.
DMAB-CPT815 is supplied as a liquid formulation in PBS only. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

Sorbin and SH3 domain-containing protein 2; ArgBP2; Arg-binding protein 2; Arg/Abl-interacting protein 2; 240023A11

Entrez Gene ID

UniProt ID