Magic™ Rabbit Anti-Human SLC7A2 Monoclonal antibody, clone 351473F4

Antibody Isotype

IgG

Clone

351473F4

Species Reactivity

Human

Immunogen

SLC7A2 fusion protein

Conjugate

Application Notes

We recommend the following antibodies for sandwich immunoassay (Capture - Detection):
DMAB-CPT1193 - DMAB-CPT1194
Cytometric Bead Array: 0.313-40 ng/mL

General Notes

This product (Catalog No. DMAB-CPT1193) is a rabbit-derived monoclonal antibody raised against human SLC7A2. It has been affinity purified by Protein A. Solute carrier family 7 member 2 (SLC7A2), also known as CAT2, is a member of the solute carrier superfamily. It functions as a cationic amino acid transporter, which can transport cationic amino acids (arginine, lysine and ornithine) into the cytosol and regulate inflammation (PMID: 35152203). It has been shown that lower SLC7A2 expression is associated with worse prognosis of ovarian cancer and hepatocellular carcinoma (PMID: 34108444; 32647070), and SLC7A2 deficiency in inflammatory bowel tissues increases the risk of inflammation-associated colon tumorigenesis.
DMAB-CPT1193 is suitable for use in Cytometric Bead Array (0.313-40 ng/mL) application.
DMAB-CPT1193 is supplied as a liquid formulation in PBS only. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

ATRC2; CAT 2; CAT2; HCAT2; SLC7A2; Solute carrier family 7 member 2

Entrez Gene ID

UniProt ID