Anti-Human Siglec-8 Monoclonal antibody

Antibody Isotype

IgG4, kappa

Species Reactivity

Human

Conjugate

Unconjugated

Application Notes

ELISA, FACS, FuncS, Reference antibody
Each laboratory should determine an optimum working titer for use in its particular application.
Other applications have not been tested but use in such assays should not necessarily be excluded.

General Notes

Lirentelimab (AK002) is a humanized IgG1 monoclonal antibody that targets sialic acid-binding Ig-like lectin 8 (SIGLEC8). Lirentelimab induces cell apoptosis of IL-5-activated eosinophils and inhibits IgE-mediated mast cell activation. Lirentelimab can be used for the research of eosinophilic gastritis and duodenitis.

Alternative Names

Lirentelimab; AK002; sialic acid binding immunoglobulin-like lectin-8; sialic acid binding Ig like lectin 8; Siglec-8; SIGLEC8

We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More