Magic™ Rabbit Anti-Human SIAH1 Monoclonal antibody, clone 351488I8

Antibody Isotype

IgG

Clone

351488I8

Species Reactivity

Human

Immunogen

SIAH1 fusion protein

Conjugate

Application Notes

We recommend the following antibodies for sandwich immunoassay (Capture - Detection):
DMAB-CPT1039 - DMAB-CPT1040
Cytometric Bead Array: 0.625-20 ng/mL

General Notes

This product (Catalog No. DMAB-CPT1039) is a rabbit-derived monoclonal antibody raised against human SIAH1. It has been affinity purified by Protein A. SIAH1, also named as HUMSIAH, Siah-1a and Siah-1S(21kd), belongs to the SINA (Seven in absentia) family. SIAH1 is known to cause indirect degradation of beta-catenin through formation of a complex with Siah-interacting protein (SIP), Skp1 and Ebi. SIAH1 can form heterodimer or homodimer such as Siah-1*Siah-1(70 or 62kd), Siah-1*Siah-1S(42kd) and Siah-1S*Siah-1S(51-56kd). Importantly, results from in vitro soft agar assay demonstrated that Siah-1S displays a promotion effect on cells tumorigenicity.
DMAB-CPT1039 is suitable for use in Cytometric Bead Array (0.625-20 ng/mL) application.
DMAB-CPT1039 is supplied as a liquid formulation in PBS only. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

FLJ08065; hSIAH1; HUMSIAH; Seven in absentia homolog 1; Siah 1; Siah 1a; SIAH1

Entrez Gene ID

UniProt ID