Magic™ Rabbit Anti-Human SFXN1 Monoclonal antibody, clone 351428D7

Antibody Isotype

IgG

Clone

351428D7

Species Reactivity

Human

Immunogen

SFXN1 fusion protein

Conjugate

Application Notes

We recommend the following antibodies for sandwich immunoassay (Capture - Detection):
DMAB-CPT971 - DMAB-CPT972
Cytometric Bead Array: 0.313-40ng/mL

General Notes

This product (Catalog No. DMAB-CPT971) is a rabbit-derived monoclonal antibody raised against human SFXN1. It has been affinity purified by Protein A. SFXN1, the founding member of the SLC56 family, was identified by positional cloning of the mutation in the flexed-tail mouse model with sideroblastic anemia. SFXN1 was recently identified as a mitochondrial serine transporter essential for one-carbon (1C) metabolism, a process in which folate species are generated and used in biosynthetic pathways required for cell proliferation. In HEK293 cells, SFXN1 is the most abundant isoform among the SFXNs.
DMAB-CPT971 is suitable for use in Cytometric Bead Array (0.313-40ng/mL) application.
DMAB-CPT971 is supplied as a liquid formulation in PBS only. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

FLJ12876; SFXN1; sideroflexin 1; TCC; Tricarboxylate carrier protein

Entrez Gene ID

UniProt ID