Magic™ Rabbit Anti-Human SESN2 Monoclonal antibody, clone 351145H6

Antibody Isotype

IgG

Clone

351145H6

Species Reactivity

Human

Immunogen

Sestrin 2 fusion protein

Conjugate

Application Notes

We recommend the following antibodies for sandwich immunoassay (Capture - Detection):
DMAB-CPT825 - DMAB-CPT826
Cytometric Bead Array: 0.625-20 ng/mL

General Notes

This product (Catalog No. DMAB-CPT825) is a rabbit-derived monoclonal antibody raised against human SESN2. It has been affinity purified by Protein A. SESN is a family of highly conserved, stress-inducible genes that can defend the cell against oxidative damage and oncogenic signaling. SESN2,which belongs to the SESN family, has been implicated as a tumor suppressor that can inhibit angiogenesis and promote autophagy, underscoring the importance of elucidating the molecular mechanism by which SESN2 regulates pathways of metabolism and survival.(PMID:22363791). Sesn2 encodes a 480 amino acid protein which can run as a 60 kDa band on SDS-polyacrylamide gel electrophoresis.
DMAB-CPT825 is suitable for use in Cytometric Bead Array (0.625-20 ng/mL) application.
DMAB-CPT825 is supplied as a liquid formulation in PBS only. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

DKFZp761M0212; DKFZp761M02121; HI95; SES2; SESN2; SEST2; sestrin 2; Sestrin2

Entrez Gene ID

UniProt ID