Specifications
Species Reactivity
Human, Mouse, Rat, Chicken, Bovine, Canine
Immunogen
A synthetic peptide corresponding to the epitope -VETFP- with a single phosphorylation site Thr396 of human RockII protein. This sequence is identical among human, mouse, rat, chicken, dog and bovine.
Applications
Application Notes
WB: 0.1-1 ug/mL; ELISA: 0.01-0.1 ug/mL; IP: 2-5 ug/mL; IHC: 2-10 ug/mL
Target
Alternative Names
ROCK2; ROCK-II; rho-associated protein kinase 2; p164 ROCK-2
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.
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Citations
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Nichols, RJ; Dzamko, N; et al. Substrate specificity and inhibitors of LRRK2, a protein kinase mutated in Parkinson's disease. BIOCHEMICAL JOURNAL 424:47-60(2009).
Park, SY; Song, HJ; et al. Participation of Rho-associated kinase in electrical stimulated and acetylcholine-induced contraction of feline esophageal smooth muscle. EUROPEAN JOURNAL OF PHARMACOLOGY 607:220-225(2009).