Application: We recommend the following antibodies for sandwich immunoassay (Capture - Detection): DMAB-CPT813 - DMAB-CPT814
Summary
Specifications
Antibody Isotype
IgG
Clone
341555F3
Species Reactivity
Human
Immunogen
OPRM1 fusion protein
Conjugate
Unconjugated
Applications
Application Notes
We recommend the following antibodies for sandwich immunoassay (Capture - Detection): DMAB-CPT813 - DMAB-CPT814 Cytometric Bead Array: 1.25-20 ng/mL
General Notes
This product (Catalog No. DMAB-CPT814) is a rabbit-derived monoclonal antibody raised against human OPRM1. It has been affinity purified by Protein A. OPRM1 (also known as Mu opioid receptor, MOR1, MOP) is a G protein-coupled receptor that mediates the physiological effects of endogenous opioids as well as the structurally distinct opioid alkaloids including morphine and etorphine (PMID: 9618555). Mu opioid receptor modulates a wide range of physiological functions, particularly involved in the control of pain perception and reward properties (PMID: 30483121). Mu opioid receptor is the principal target of opioid drugs. It is encoded by OPRM1 gene and multiple transcript variants encoding different isoforms have been found. Mu opioid receptor contains sites for N-linked glycosylation. The transcript variants and variations of glycosylation may result in migrating bands of Mu opioid receptor. DMAB-CPT814 is suitable for use in Cytometric Bead Array (1.25-20 ng/mL) application. DMAB-CPT814 is supplied as a liquid formulation in PBS only. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
Target
Alternative Names
hMOP; KIAA0403; LMOR; M OR 1; MOP; MOR; MOR 1; MOR1; Mu opiate receptor; Mu opioid receptor; Mu type opioid receptor; opioid receptor; mu 1; OPRM; OPRM1
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