Magic™ Rabbit Anti-Human MAEA Monoclonal antibody, clone 351108C3

Antibody Isotype

IgG

Clone

351108C3

Species Reactivity

Human

Immunogen

MAEA fusion protein

Conjugate

Application Notes

We recommend the following antibodies for sandwich immunoassay (Capture - Detection):
DMAB-CPT747 - DMAB-CPT748
Cytometric Bead Array: 1.25-100 ng/mL

General Notes

This product (Catalog No. DMAB-CPT747) is a rabbit-derived monoclonal antibody raised against human MAEA. It has been affinity purified by Protein A. MAEA (macrophage erythroblast attacher) is a core component of the CTLH E3 ubiquitin-protein ligase complex. MAEA is required for normal cell proliferation and plays a role in erythroblast enucleation during erythrocyte maturation and in the development of mature macrophages. N-terminus MAEA and full-length MAEA are mostly expressed in nuclear and can be detected at low level in the cytoplasm of some cells, while C-terminus MAEA can be detected in the cytoplasm and nucleoli within the nucleus. MAEA mediates the attachment of erythroid cell to mature macrophages which can inhibit erythroid cell apoptosis. The expression of MAEA may be associated with the type 2 diabetes mellitus.
DMAB-CPT747 is suitable for use in Cytometric Bead Array (1.25-100 ng/mL) application.
DMAB-CPT747 is supplied as a liquid formulation in PBS only. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

EMLP; EMP; HLC 10; MAEA; PIG5; macrophage erythroblast attacher

Entrez Gene ID

UniProt ID