Product Overview
Recombinant Leukocyte immunoglobulin-like receptor subfamily B member 1 is produced by our Mammalian expression system and the target gene encoding Gly24-His458 is expressed with a mFc tag at the C-terminus.
Endotoxin
Less than 0.1 ng/μg (1 EU/μg) as determined by LAL test.
Alternative Names
Leukocyte immunoglobulin-like receptor subfamily B member 1; LIR-1; Leukocyte immunoglobulin-like receptor 1; CD85 antigen-like family member J; Immunoglobulin-like transcript 2; ILT-2; Monocyte/macrophage immunoglobulin-like receptor 7; MIR-7; CD85j; LILRB1; ILT2; LIR1; MIR7
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Buffer
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Storage
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Reconstitution
Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/mL. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Introduction
Leukocyte immunoglobulin-like receptor subfamily B member 1 (LILRB1) is known as CD85j. It is a receptor for class I MHC antigens, the protein can be recognized by a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles. It expressed in B cells, monocytes and various dendritic cell (DC) subsets including myeloid, plasmacytoid and tolerogenic DCs. Diseases associated with LILRB1 include Alzheimer's Disease 12 and Severe Pre-Eclampsia.
Keywords
Leukocyte immunoglobulin-like receptor subfamily B member 1; LIR-1; Leukocyte immunoglobulin-like receptor 1; CD85 antigen-like family member J; Immunoglobulin-like transcript 2; ILT-2; Monocyte/macrophage immunoglobulin-like receptor 7; MIR-7; CD85j; LILRB1; ILT2; LIR1; MIR7
Citations
Publication ()
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