Native human leukocyte elastase purified from human neutrophils
Nature
Native
Tag/Conjugate
Unconjugated
Molecular Weight
30 kDa
Purity
> 90% , as determined by SDS-PAGE
Storage
2-8°C short term, -20°C long term
Introduction
Elastase, part of the serine protease superfamily, is a 30kDa protein expressed in neutrophil granules with a 267 amino acid residue. It undergoes posttranslational modification at both termini during processing of the enzyme. Reported to be present as a marker in IBD, it has also been implicated in congenital and cyclic neutropenia. Elastase reportedly could be used as a biomarker for the progression of cancer, specifically in colorectal cancer.
Keywords
Elastase; Neutrophil; Human leukocyte elastase
Citations
Publication ()
Have you cited DAG-WT298 in a publication? Let us know and earn a reward for your research.
A: No. The elastase is not proteolytically active. It is purified for autoantigen applications, and the protease activity is intentionally inactivated during the purification process.
Customer Reviews
My Review for Native Human Leukocyte Elastase
Creative Diagnostics products are for RESEARCH USE ONLY, please make sure your review is research based.
Required fields are marked with *
Terms and conditions:
We will select high-quality review customers and offer a $30 coupon for your next purchase.
All product reviews must be submitted in the English language.
Creative Diagnostics will not share any personal information of applicants, and all information will be treated with strict confidentiality and will not be sold or disclosed to a third party.
COA
Publication 
Loading ......
