Magic™ Rabbit Anti-Human HSPA2 Monoclonal antibody, clone 351532B3

Antibody Isotype

IgG

Clone

351532B3

Species Reactivity

Human; Mouse

Immunogen

HSPA2 fusion protein

Conjugate

Application Notes

We recommend the following antibodies for sandwich immunoassay (Capture - Detection):
DMAB-CPT1143 - DMAB-CPT1144

General Notes

This product (Catalog No. DMAB-CPT1143) is a rabbit-derived monoclonal antibody raised against human HSPA2. This antibody exhibits cross-reactivity with Human HSPA2 from mouse. It has been affinity purified by Protein A. Human HSPA2 is a member of the HSPA (HSP70) family of heat-shock proteins, encoded by the gene originally described as testis-specific. Recently, it has been reported that HSPA2 can be also expressed in human somatic tissues in a cell-type specific manner. HSPA2 is a cytosol/nuclear protein able to translocate between cytoplasm and nucleus. At physiological temperature, the HSPA2 was localized primarily in cytoplasm whereas, during heat shock, localization shifted to nucleus and nucleoli (PMID: 18452162). HSPA2 is involved in sperm maturity, function and fertility. Aberrant expression of HSPA2 in testes has been connected with male infertility. Recently, HSPA2 has attracted increased interest due to its possible involvement in carcinogenesis of non-testicular tissues.
DMAB-CPT1143 is suitable for use in CBA(Cap), ELISA(Cap) applications.
DMAB-CPT1143 is supplied as a liquid formulation in PBS only. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

HSP70 2; Heat shock-related 70 kDa protein 2; Heat shock protein family A member 2; Heat shock 70 kDa protein 2; 240421A2

Entrez Gene ID

UniProt ID