Specificity: Nb43 binds to full-length mGlu1. Nb43 is tried to stabilize full-length mGlu1 after mutating seven Nb43 binding residues in the VFT of mGlu1 to the corresponding residues in mGlu5.
Isotype: VHH
Application: ELISA, Crystallography
Multiplex assay ready: PBS only formulation, ready for custom conjugation.
Summary
Specifications
Antibody Isotype
VHH
Clone
Nb43
Species Reactivity
Human
Immunogen
Human GRM1
Conjugate
Unconjugated
Applications
Application Notes
Suitable for use in ELISA, Crystallography. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
General Notes
Recombinant monoclonal antibody to Human GRM1. Produced utilizing a recombinant platform technology. It can be used in ELISA, Crystallography.
Target
Alternative Names
Metabotropic glutamate receptor 1; mGlu1; GRM1
Citations
Publication ()
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References
Structural insights into the activation initiation of full-length mGlu1.
(2021) Protein Cell 12: 662-667
Authors: Zhang, J., Qu, L., Wu, L., Tang, X., Luo, F., Xu, W., Xu, Y., Liu, Z.J., Hua, T.
COA
Publication 
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