Alternative Names
C9orf155; GOLPH2; Golgi membrane protein GP73; Golgi phosphoprotein 2
Purity
> 90% , as determined by SDS-PAGE
Format
Liquid/Lyophilized Powder
Concentration
Batch dependent - please inquire should you have specific requirements.
Buffer
0.01 M PBS, pH 7.4
Storage
Store at 2-8°C up to 7 days, -20°C for long term. Avoid freeze / thaw cycles.
Introduction
Golgi membrane protein 1, also known as Golgi membrane protein GP73, Golgi phosphoprotein 2 and GOLM1, is a protein which belongs to theGOLM1 / CASC4 family. GOLM1 is widely expressed. It is highly expressed in colon, prostate, trachea and stomach. It is expressed at lower level in testis, muscle, lymphoid tissues, white blood cells and spleen. It is predominantly expressed by cells of the epithelial lineage. GOLM1 is expressed at low level in normal liver. Expression significantly increases in virus (HBV, HCV) infected liver. Expression of GOLM1 does not increase in liver disease due to non-viral causes (alcohol-induced liver disease, autoimmune hepatitis). Increased expression in hepatocytes appears to be a general feature of advanced liver disease. In liver tissue from patients with adult giant-cell hepatitis (GCH), GOLM1 is strongly expressed in hepatocyte-derived syncitial giant cells. GOLM1 is constitutively expressed by biliary epithelial cells but not by hepatocytes.
Antigen Description
DNA sequence encoding the human GOLM1 (Val40~Leu401) was fused with the N-terminal His Tag
Citations
Publication ()
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COA
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