Product Overview
Recombinant human Galectin-3 antigen with an N-terminal histidine tag.
Alternative Names
LGALS3; Galectin-3; Galectin 3; Mac-2
Purity
>90% as determined by reduced SDS-PAGE.
Buffer
50 mM Tris-HCl, 150 mM NaCl, 1 mM TCEP, pH 7.5
Preservative
0.095 % Sodium azide
Storage
Unspecified, storage at 2-8 °C, do not freeze
Introduction
Galectin-3 (Mac-2 antigen, IgE-binding protein, L-29, or CBP30) is a soluble lectin that binds to β-galactoside sugars found on several proteins. It is a pro-inflammatory and pro-fibriotic marker involved in fibrosis of various organs, including heart, vessels, lungs, liver, and kidneys. Its expression is upregulated in chronic inflammatory diseases, heart failure, hypertension and atherosclerotic lesions, and it is involved in several pathophysiological processes including cancer, liver cirrhosis, and diabetes
mellitus.
Keywords
LGALS3; Galectin-3; Galectin 3; Mac-2
Citations
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