Application: We recommend the following antibodies for sandwich immunoassay (Capture - Detection): DMAB-CPT1207 - DMAB-CPT1208
Summary
Specifications
Antibody Isotype
IgG
Clone
351619C22
Species Reactivity
Human
Immunogen
C10orf97 fusion protein
Conjugate
Unconjugated
Applications
Application Notes
We recommend the following antibodies for sandwich immunoassay (Capture - Detection): DMAB-CPT1207 - DMAB-CPT1208 Cytometric Bead Array: 0.625-40 ng/mL
General Notes
This product (Catalog No. DMAB-CPT1208) is a rabbit-derived monoclonal antibody raised against human FAM188A. It has been affinity purified by Protein A. MINDY3 (also known as FAM63B) is a deubiquitinating enzyme (DUB) localized to the endoplasmic reticulum and belongs to the MINDY family. This protein specifically recognizes and cleaves lysine 48 (K48)-linked ubiquitin chains, which serve as the primary signal targeting proteins for proteasomal degradation, thereby playing a critical role in regulating protein stability. Research indicates that MINDY3 influences various cellular processes through its deubiquitination activity, including endoplasmic reticulum-associated degradation (ERAD), cellular stress response, and cell cycle regulation. Dysregulation of its function is closely associated with pathological processes such as cancer and neurodegenerative diseases, making it a potential target for therapeutic research. DMAB-CPT1208 is suitable for use in Cytometric Bead Array (0.625-40 ng/mL) application. DMAB-CPT1208 is supplied as a liquid formulation in PBS only. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
Target
Alternative Names
chromosome 10 open reading frame 97; C10orf97; CARP; DERP5; FAM188A; FLJ13397; MST126; MSTP126; my042; Protein CARP; Protein FAM188A; RP11 394I23.1; MINDY3; FAM63B
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