Magic™ Rabbit Anti-Human EP300 Monoclonal antibody, clone 341470F7

Antibody Isotype

IgG

Clone

341470F7

Species Reactivity

Human

Immunogen

Peptide

Conjugate

Application Notes

We recommend the following antibodies for sandwich immunoassay (Capture - Detection):
DMAB-CPT875 - DMAB-CPT876
Cytometric Bead Array: 0.313-10 ng/mL

General Notes

This product (Catalog No. DMAB-CPT876) is a rabbit-derived monoclonal antibody raised against human EP300. It has been affinity purified by Protein A. p300 is a 300 kDa global transcriptional coactivator with histone acetyltransferase (HAT) activity. p300 binds to chromosomal histones and modulates the chromatin conformation by acetylation of its histones, leading to activation of various gene transcriptions. p300 plays a critical role in DNA repair synthesis after DNA damage induced by ultraviolet or radiation. p300 is overexpressed in various types of cancer, which is associated with worse patient outcomes.
DMAB-CPT876 is suitable for use in Cytometric Bead Array (0.313-10 ng/mL) application.
DMAB-CPT876 is supplied as a liquid formulation in PBS only. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

E1A associated protein p300; E1A binding protein p300; EP300; Histone acetyltransferase p300; KAT3B; p300; p300 HAT

Entrez Gene ID

UniProt ID