A DNA sequence encoding the Helicobacter pylori CagA (a.a 600 to a.a. 1183) was expressed with a polyhistidine tag at the C-terminus.
Target
H. pylori CagA
Nature
Recombinant
Tag/Conjugate
His
Molecular Weight
70 kDa
Alternative Names
Helicobacter pylori CagA; H. pylori CagA
Purity
> 90% , as determined by SDS-PAGE
Format
Liquid
Concentration
Batch dependent - please inquire should you have specific requirements
Buffer
20 mM Trtis-HCl pH 8.0; 500 mM NaCl; 8M Urea
Preservative
None
Storage
Store at -80°C. Avoid multiple freeze/thaw cycles.
Introduction
Helicobacter pylori virulence factor CagA (cytotoxin-associated gene A) is a 120–145kDa protein encoded on the 40kb cag pathogenicity island (PAI). H. pylori strains can be divided into CagA positive or negative strains. Approximately 60% of H. pylori strains isolated in Western countries carry cag PAI, whereas almost all of the East Asian isolates are cag PAI-positive.
Keywords
Helicobacter pylori; CagA; Hp
Citations
Publication ()
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