Magic™ Mouse Anti-GBS Ⅲ monoclonal antibody, clone J7231

Synchronous occurrence of Guillain-Barre syndrome (GBS) and acute transverse myelitis (ATM) happens very rarely in childhood. Only a few cases of these conditions occurring simultaneously have been reported and represent a diagnostic challenge. We describe a case of a 17-year-old male presenting with acute onset of bilateral symmetrical numbness and tingling starting in the feet that rapidly ascended to the legs with associated motor weakness, associated with a sensory level and urinary retention. Albuminocytologic dissociation on cerebrospinal fluid (CSF) analysis was consistent with GBS. MRI spine revealed an area of increased T2 signal involving the dorsal aspect of the left side of the cord at the C7 level. The patient was treated with IV methylprednisolone and IV immunoglobulin with significant improvement. This report emphasizes the rarity of this synchronous occurrence in children and the need for further reports to understand the mechanism and better treatment approaches.

This empirical study attempts to examine the effect of environmental orientation (EO) on environmental performance (EP). Mediating role of green business strategies (GBS) in this relationship is also tested. Furthermore, the moderating role of top management environmental awareness (TMEA) in the relationship between EO and GBS is also analyzed. Simple random sampling technique was used for data collection purposes. Data was collected from managers of 126 manufacturing industries of Pakistan. These industries include pharmaceutical instruments, office machinery, furniture and fixtures, electrical equipment, and automobile accessories. Correlation, linear regression and structural equation modeling techniques were used for data analysis. Findings revealed a direct effect of EO on GBS and EP. In addition, the results confirm that GBS positively mediate between EO and EP. It also founds that TMEA strengthens the direct effect of EO on GBS. Although the empirical evidence is reasonably established that EO has a substantial contribution for EP, however, in the existing studies, there is a lack of discussion on the links between EO, development of GBP and improvement of EP in the context of manufacturing industries of the developing countries like Pakistan. The results of the study suggest that organizations are required to put more attention towards stakeholders' requirements and strategies that ensure the protection of the natural environment. Hence, EO in term of internal orientation and external orientation are pertinent to formulate GBS in order to improve EP in a more appropriate way. The data for the study was collected from manufacturing businesses; therefore, the result of the current study may not be generalizable to all industries. (C) 2020 Elsevier Ltd. All rights reserved.