Application note: Suitable for use in ELISA, Inhibition. It inhibits plasminogen activation by streptokinase, tPA and uPA.
Specificity: Kringle 5 B-chain
Clonality: Monoclonal
Summary
Specifications
Antibody Isotype
IgG1
Clone
141
Species Reactivity
Human
Immunogen
Human plasminogen
Conjugate
Unconjugated
Applications
Application Notes
Suitable for use in ELISA, Inhibition Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
General Notes
Plasminogen, precursor of the active protease plasmin, is a single chain glycoprotein of 92 kDa. Found in plasma at a concentration of 200 ug/ml, it contains 5 disulfide-bonded structures termed "kringles" and a serine protease domain at the carboxy-terminus. Plasmin is primarily responsible for digesting fibrin clots. This clone binds human plasminogen kringle 5 B-chain in solid-phase ELISA. It inhibits plasminogen activation by streptokinase, tPA and uPA.
Citations
Publication ()
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