Batch dependent - please inquire should you have specific requirements
Buffer
PBS buffer
Preservative
None
Storage
2-8°C short term, -20°C long term
Introduction
Fluorouracil is an antineoplastic anti-metabolite. Anti-metabolites masquerade as purine or pyrimidine - which become the building blocks of DNA. They prevent these substances from becoming incorporated into DNA during the "S" phase (of the cell cycle), stopping normal development and division. Fluorouracil blocks an enzyme which converts the cytosine nucleotide into the deoxy derivative. In addition, DNA synthesis is further inhibited because Fluorouracil blocks the incorporation of the thymidine nucleotide into the DNA strand.
Keywords
Fluorouracil; 5FU; Antineoplastic; Adrucil
Citations
Publication ()
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COA
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