Anti-Etanercept monoclonal antibody

Antibody Isotype

IgG1, κ

Clone

5I2

Immunogen

Etanercept

Conjugate

Unconjugated

Application Notes

Suitable for use in PK bridging ELISA.
We recommend the following for sandwich ELISA (Capture - Detection):
CABT-ZB205 - CABT-ZB206
Recommended Working Concentration: 0.005-1 μg/ml

General Notes

We recommend the following antibody pair to develop a pharmacokinetic (PK) bridging assay to measure free drug: CABT-ZB205 - CABT-ZB206
CABT-ZB206 is recommended for use as a detection antibody when paired with CABT-ZB205 as a capture antibody.
Etanercept with trade name Enbrel, is an FDA-approved drug to treat rheumatoid arthritis, juvenile idiopathic arthritis and psoriatic arthritis, plaque psoriasis and ankylosing spondylitis. Etanercept is a fusion protein made from the combination of two naturally occurring soluble human 75-kilodalton TNF receptors linked to an Fc portion of an IgG1. Etanercept treats autoimmune diseases by interfering with tumor necrosis factor-alpha (TNFα, a soluble inflammatory cytokine) by acting as a TNFα inhibitor.

Alternative Names

Mouse monoclonal antibody to Etanercept/Enbrel; Etanercept; Enbrel

We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More