Product Overview
C-terminal 6x His tagged nucleoprotein (NP) (amino acid 396-738) of Zaire Ebolavirus (isolate H.sapiens wt/GIN/2014/Kissidougou-C15) (GenBank No. AHX24646.1)
Endotoxin
<0.01 EU per 1 μg of the protein by LAL test
Alternative Names
EBOV; Zaire Ebolavirus; EBOV Nucleoprotein; EBOV NP; Ebolavirus
Purity
≥ 95% (by SDS PAGE)
Storage
Store at -20°C; Stable for 6-months from the date of shipment when kept at 4°C. Nonhazardous, no MSDS required.
Introduction
The Ebola virus (EBOV) is a mononegavirus which contains a 19 kb single-stand RNA encoding seven proteins: nucleoprotein (NP), viral protein (VP) 35, VP40, glycoprotein (GP), VP30, VP24, and RNA polymerase (L). VP30, VP35, NP, and L are the 4 virion structural proteins. VP40, GP, and VP24 are the 3 membrane-associated proteins.
NP plays an important role in the replication of the viral genome and is essential for formation of the nucleocapsid. The produced NP protein (~45 kDa) is derived from the sequence of a recent Zaire Ebolavirus (ZEBOV) isolate from 2014 outbreak in western Africa
Keywords
EBOV; Zaire Ebolavirus; EBOV Nucleoprotein; EBOV NP; Ebolavirus
Citations
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