Human EIF4A2 peptide

Nature

Synthetic

Tag/Conjugate

Unconjugated

Format

Liquid

Preservative

None

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request.

Gene ID

1974

UniProt ID

Q14240

Antigen Description

Eukaryotic initiation factor 4A plays an important role in the binding of mRNA to the 43S preinitiation complex when protein synthesis begins. Two highly homologous forms of functional EIF4A genes, Eif4a1 and Eif4a2, have been isolated in mice; yeast cells also possess 2 EIF4A genes, TIF1 and TIF2. The murine Eif4a and yeast TIF genes appear to belong to a DEAD-box gene family, whose members exhibit extensive amino acid similarity and contain the asp-glu-ala-asp (DEAD) sequence. DEAD-box genes have been identified in species ranging from E-coli to humans. Their function appears to be related to transcriptional/translational regulation (referenced from OMIM).

Function

ATP binding; ATP-dependent helicase activity; helicase activity; poly(A) RNA binding; protein binding; translation initiation factor activity;

Synonyms

EIF4A2; eukaryotic translation initiation factor 4A2; DDX2B; EIF4A; EIF4F; BM-010; eIF4A-II; eIF-4A-II; eukaryotic initiation factor 4A-II; ATP-dependent RNA helicase eIF4A-2; eukaryotic translation initiation factor 4A, isoform 2;