Anti-eIF2B2 monoclonal antibody (DMABT-H13620)

Mouse anti-Human eIF2B2 monoclonal antibody for WB, IHC, sELISA, ELISA Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
6C23-F20
Species Reactivity
Human
Immunogen
EIF2B2 (AAH00494,2a.a. ~ 351 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated

Target


Alternative Names
EIF2B2; eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa; eukaryotic translation initiation factor 2B, subunit 2 (beta, 39kD); translation initiation factor eIF-2B subunit beta; EIF 2Bbeta; EIF2B
Entrez Gene ID
UniProt ID

Product Background


Pathway
Cap-dependent Translation Initiation, organism-specific biosystem; Eukaryotic Translation Initiation, organism-specific biosystem; Gene Expression, organism-specific biosystem; Metabolism of proteins, organism-specific biosystem; RNA transport, organism-specific biosystem; RNA transport, conserved biosystem; Recycling of eIF2:GDP, organism-specific biosystem;

Citations


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References


Shimada, S; Miya, K; et al. An unmasked mutation of EIF2B2 due to submicroscopic deletion of 14q24.3 in a patient with vanishing white matter disease. AMERICAN JOURNAL OF MEDICAL GENETICS PART A 158A:1771-1777(2012).
Sambati, L; Agati, R; et al. Vanishing white matter disease: an Italian case with A638G mutation in exon 5 of EIF2B2 gene, an unusual early onset and a long course. NEUROLOGICAL SCIENCES 34:1235-1238(2013).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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