Molecular Weight
app. 44 kDa
Alternative Names
cefaclor; Cephaclor; Ceclor; Cefaclor anhydrous; Cefaclorum; Kefral
Purity
chromatography, dialysis
Concentration
1 mg/mL working concentration
Reconstitution
Reconstitute with 1 ml PBS without azide.
Introduction
Cefaclor is a cephalosporin bearing chloro and (R)-2-amino-2-phenylacetamido groups at positions 3 and 7, respectively, of the cephem skeleton. It has a role as an antibacterial drug and a drug allergen.
Cefaclor Anhydrous is the anhydrous form of cefaclor, a beta-lactam, second-generation cephalosporin with antibacterial activity. Cefaclor binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.
Antigen Description
Cefaclor, covalently linked to horseradish peroxidase
Keywords
drug-HRP conjugate, drug-conjugate, Cefaclor HRP conjugate
Citations
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