Carnosine ELISA Kit

Sample

serum, plasma and other biological fluids

Species Reactivity

Human

Intended Use

This ELISA kit applies to the in vitro quantitative determination of Carnosine concentrations in serum, plasma and other biological fluids.

Storage

An unopened kit can be stored at 2-8°C for 1 month. If the kit is not used within 1 month, store the items separately according to the following conditions once the kit is received.

Precision

Intra-assay Precision (Precision within an assay): 3 samples with low, mid range and high level Car were tested 20 times on one plate, respectively.
Inter-assay Precision (Precision between assays): 3 samples with low, mid range and high level Car were tested on 3 different plates, 20 replicates in each plate.

Detection Range

15.63-1000 ng/mL

Sensitivity

9.38 ng/mL

General Description

Carnosine is a dipeptide composed of the amino acids, histidine and alanine. It is found in relatively high concentrations in several body tissues - most notably in skeletal muscle, heart muscle, and brain. The exact biological role of carnosine is not entirely understood. However, animal studies have demonstrated that carnosine possesses strong and specific antioxidant properties, protects against radiation damage, improves the function of the heart, and promotes wound healing. Carnosine has been suggested to be the water-soluble counterpart to vitamin E in protecting cell membranes from oxidative damage. Other suggested roles for carnosine include actions as a neurotransmitter, modulator of enzyme activities, and chelator of heavy metals.